IMEGLIMIN HYDROCHLORIDE

IMEGLIMIN HYDROCHLORIDE

Biochem/physiol Actions

Imeglimin is a first-in-class oral glucose-lowering agent whose mechanism of action targets mitochondrial bioenergetics, resulting in increased insulin secretion in response to glucose, improved glucose uptake by skeletal muscle, and suppression of gluconeogenesis. Imeglimin has been shown to decrease reactive oxygen species overproduction and delay mPTP opening, preventing cell death during oxidative stress, protecting beta-cells. In an animal model, it has been shown to reduce metabolic syndrome-related diabetic cardiomyopathy.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576265 IMEGLIMIN HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C H2O: 2 mg/mL, clear powder ≥98% (HPLC)
£725.68 (exc VAT) per EACH
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3576266 IMEGLIMIN HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C H2O: 2 mg/mL, clear powder ≥98% (HPLC)
£181.07 (exc VAT) per EACH
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