Hyaluronidase from sheep testes, Type II, lyophilized powder, >=300 units/mg solid

Application

Hyaluronidase from sheep testes has been used:in flow cytometryin the isolation of putative spermatogonial stem cells (SSCs)to study the effects of magnetic stimulation in magnetic hydrogel propertiesin immunohistochemistry to visualize collagen type II distributionto expose group-III auditory neurons of Muller?s organ for patch-clamp recordingsfor the degeneration of hydrogels

Biochem/physiol Actions

These enzymes randomly cleave β-N-acetylhexosamine-(1−4)-glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.

General description

Hyaluronidase is a hyaluronic acid-metabolizing enzyme. It is found in the venoms of snake, honeybee and hymenoptera. Hyaluronidase degrades hyaluronic acid (HA), which enhances membrane permeability, lowers viscosity and increases tissue permeability. It enhances the diffusion of local anesthetics, lowers the size of myocardial infarction, improves the effects of anticancer drugs and prevents perineal trauma during spontaneous delivery.

Other Notes

View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer

Packaging

100, 500 mg in poly bottle

1, 5 g in poly bottle

Physical form

Lyophilized powder containing lactose

Unit Definition

One unit will cause a change in % transmittance at 600 nm of 0.330 per minute at pH 5.35 at 37 °C in a 2.0 mL reaction mixture (45 minute assay).

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Code Description Quality Level Manufacturer Storage Temp. Form Price Quantity
3579670 Hyaluronidase from sheep testes, Type II, lyophilized powder, >=300 units/mg solid 200 SIGMA-ALDRICH −20°C lyophilized powder
£76.19 (exc VAT) per 100MG
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3579671 Hyaluronidase from sheep testes, Type II, lyophilized powder, >=300 units/mg solid 200 SIGMA-ALDRICH −20°C lyophilized powder
£431.79 (exc VAT) per 1G
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3579672 Hyaluronidase from sheep testes, Type II, lyophilized powder, >=300 units/mg solid 200 SIGMA-ALDRICH −20°C lyophilized powder
£250.71 (exc VAT) per 500MG
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3579673 Hyaluronidase from sheep testes, Type II, lyophilized powder, >=300 units/mg solid 200 SIGMA-ALDRICH −20°C lyophilized powder
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