HX531

HX531

Biochem/physiol Actions

HX-531 is a potent antagonist of the retinoid X receptor (RXR) with an IC50 value of 18 nM. HX531 has been used in many studies of the various effects of retinoids and RXR activity in diseases such as diabetes, Parkinson′s disease, often as a control for agonists such as Bexarotene. It was recently shown to promote white adipogenic differentiation and inhibit both basal and Bexarotene-induced brown adipogenic differentiation.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575912 HX531 yellow to orange SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£429.00 (exc VAT) per 25MG
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3575913 HX531 yellow to orange SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£124.10 (exc VAT) per 5MG
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