HA15

HA15

Biochem/physiol Actions

HA15 is a selective ligand of BiP/GRP78/HSPA5 chaperone that increases ER stress, leading to autophagic and apoptotic cell death in varies cancer cell lines including melanoma cells. HA15 inhibits inhibit the ATPase activity of BiP. HA15 inhibits tumor development in mice injected with A375 melanoma cells.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575838 HA15 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£575.25 (exc VAT) per 25MG
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3575839 HA15 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£121.32 (exc VAT) per 5MG
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