FastWells reagent barriers are sticky, flexible silicone gaskets that form hydrophobic barriers around specimens without messy adhesives or special slides. Gaskets may be stacked to increase depth and volume.FastWells provide rapid isolation of cells and tissues on slides or coverslips for antibody incubations. The barriers remain sealed during agitated washing steps, preventing reagents from spilling when shaken or rocked. FastWells peel off quickly and cleanly, leaving no residue to interfere with specimen cover-slipping. They can be washed, autoclaved and reused. The barriers can also be sealed to form incubation chambers using flexible HybriSlip covers.