Fumonisin B2 from Fusarium moniliforme, sphingosine N-acyltransferase inhibitor

Application

Fumonisin B2 (FB2) from Fusarium moniliforme has been used:as a standard for the detection of FB2 by high performance liquid chromatography (HPLC) in corn based food productsused as standard in the determination of fumonisin B1 and B2 in corn and corn-based products by high-performance liquid chromatographyas a standard in the determination of mycotoxins by HPLC

Biochem/physiol Actions

Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.

General description

Mycotoxin originally isolated from Fusarium sp, which grows on corn. Produces neural tube defects and craniofacial abnormalities in fetuses. Many strains of Aspergillus niger growing naturally on grapes are capable of producing fumonisin B2, so it is now a concern for human consumption of grapes, raisins, and wine.

Fumonisin B2 (FB2) is a diester of tricarballylic acid and polyhydric alcohols.. Fumonisins B2 (FB2) does not have one or more hydroxyl groups at the C5 or C10 positions.

Packaging

1 mg in glass bottle

10 mg in glass insert

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Code Description Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3577774 Fumonisin B2 from Fusarium moniliforme, sphingosine N-acyltransferase inhibitor 100 UXDPXZQHTDAXOZ-UHFFFAOYSA-N 1S/C34H59NO14/c1-5-6-12-21(3)32(49-31(43)18-24(34(46)47)16-29(40)41)27(48-30(42)17-23(33(44)45)15-28(38)39)14-20(2)11-9-7-8-10-13-25(36)19-26(37)22(4)35/h20-27 SIGMA-ALDRICH methanol: 10 mg/mL, clear, colorless to faintly yellow powder ≥96% (TLC)
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3577775 Fumonisin B2 from Fusarium moniliforme, sphingosine N-acyltransferase inhibitor 100 UXDPXZQHTDAXOZ-UHFFFAOYSA-N 1S/C34H59NO14/c1-5-6-12-21(3)32(49-31(43)18-24(34(46)47)16-29(40)41)27(48-30(42)17-23(33(44)45)15-28(38)39)14-20(2)11-9-7-8-10-13-25(36)19-26(37)22(4)35/h20-27 SIGMA-ALDRICH methanol: 10 mg/mL, clear, colorless to faintly yellow powder ≥96% (TLC)
£653.25 (exc VAT) per 1MG
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