FROVATRIPTAN SUCCINATE MONOHYDRATE

FROVATRIPTAN SUCCINATE MONOHYDRATE

Biochem/physiol Actions

Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.

During migraine condition, frovatriptan succinate monohydrate acts on extra cerebral, intracranial arteries and prevent excessive dilation of these vessels.

Packaging

10, 50 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3574710 FROVATRIPTAN SUCCINATE MONOHYDRATE white to beige 100 CUETXFMONOSVJA-KLQYNRQASA-N 1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/ SIGMA-ALDRICH powder ≥97% (HPLC)
£142.07 (exc VAT) per 10MG
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3574711 FROVATRIPTAN SUCCINATE MONOHYDRATE white to beige 100 CUETXFMONOSVJA-KLQYNRQASA-N 1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/ SIGMA-ALDRICH powder ≥97% (HPLC)
£518.14 (exc VAT) per 50MG
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