FQI1, >=98% (HPLC)

Biochem/physiol Actions

FQI1 inhibits the DNA-binding activity of LSF, a ubiquitous transcription factor that is up regulated in many hepatocellular carcinomas (HCC). FQI1 inhibits LSF-dependent luciferase reporter expression, blocks proliferation in cancer cell lines, and induces apoptosis in liver cancer cells but is not toxic to primary hepatocytes. FQI1 also inhibits tumor growth in a mouse HCC xenograft model.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574068 FQI1, >=98% (HPLC) white to beige 100 YKSYGLXHLSPWLB-UHFFFAOYSA-N 1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20) SIGMA-ALDRICH DMSO: 10 mg/mL (clear solution) powder ≥98% (HPLC)
£412.29 (exc VAT) per 25MG
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3574069 FQI1, >=98% (HPLC) white to beige 100 YKSYGLXHLSPWLB-UHFFFAOYSA-N 1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20) SIGMA-ALDRICH DMSO: 10 mg/mL (clear solution) powder ≥98% (HPLC)
£146.25 (exc VAT) per 5MG
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