FPH2

FPH2

Biochem/physiol Actions

FPH2 (BRD-9424) induced functional proliferation of primary human hepatocytes in vitro. Human induced pluripotent stem (iPS) cells can be differentiated toward hepatocyte-like (iHep) cells, but replication is not great, and cells typically show an immature hepatic phenotype and have limited use as a renewable source of functional human hepatocytes. FPH2 induced hepatocyte doublings at a rate consistent with reported liver regeneration kinetics. FPH2 can be used in conjunction with FH1 (BRD-K4477), which induces a more mature phenotype.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574145 FPH2 white to beige 100 SIGMA-ALDRICH −20°C
£554.36 (exc VAT) per 25MG
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3574146 FPH2 white to beige 100 SIGMA-ALDRICH −20°C
£153.21 (exc VAT) per 5MG
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