Fibronectin from human plasma, liquid, 0.1% (Solution), BioReagent, suitable for cell culture

Analysis Note

Protein homogeneity is evaluated by immunoelectrophoresis.

Application

Fibronectin human plasma has been used in the determination of H2O2 consumption rate. It has also been used in coating the Sylgard® models for cell culture. It has also been used in cell adhesion and to directly pattern the protein onto the polymeric film.

Biochem/physiol Actions

Fibronectin 1 (FN1) participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis.

General description

Fibronectin 1 is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. The FN1 gene mapped to human chromosome 2q35.

Legal Information

Sylgard is a registered trademark of The Dow Chemical Company or an affiliated company of Dow

Preparation Note

This product is a 0.1% solution of fibronectin. The protein homogeneity is evaluated by immunoelectrophoresis, is endotoxin tested, and the source material was tested negative for HIV, hepatitis B and hepatitis C. In coating culture surfaces, fibronectin should be diluted in sterile balanced sterile salt solution and coated with minimal volume. Surface should then be air dried for 45 minutes at room temp and can be stored for 2-4 weeks at 2-8°C

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Code Description Quality Level Pack Manufacturer Product Line Form Price Quantity
3571645 Fibronectin from human plasma, liquid, 0.1% (Solution), BioReagent, suitable for cell culture 200 1MG SIGMA-ALDRICH BioReagent liquid
£385.00 (exc VAT) per 1MG
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3571646 Fibronectin from human plasma, liquid, 0.1% (Solution), BioReagent, suitable for cell culture 200 2MG SIGMA-ALDRICH BioReagent liquid
£474.50 (exc VAT) per 2MG
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3571647 Fibronectin from human plasma, liquid, 0.1% (Solution), BioReagent, suitable for cell culture 200 5MG SIGMA-ALDRICH BioReagent liquid
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