FEXINIDAZOLE

FEXINIDAZOLE

Biochem/physiol Actions

Anti Trypanosoma, Leishmania agent.

Fexinidazole is a potent anti-Trypanosoma agent. Trypanosoma species human protozoan pathogens are responsible for sleeping sickness and Chagas disease. In vivo, fexinidazole is oxidized to sulfoxide and sulfone metabolites that are effective in blocking the progression of the parasitic disease visceral leishmaniasis. The mechanism of action appears to be by reductive activation via an NADH-dependent nitroreductase expressed by the parasites.

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576437 FEXINIDAZOLE light yellow to dark brown SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£626.79 (exc VAT) per 25MG
-
+
3576438 FEXINIDAZOLE light yellow to dark brown SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£156.00 (exc VAT) per 5MG
-
+