Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti

Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti

Application

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used as a component of the plasma membrane resuspension buffer, inhibitor?s preservative solution (IS) and luciferase activity assay mix.

Biochem/physiol Actions

Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.

General description

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions to form an octahedral complex especially with cations. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy protects from lipid peroxidation events in liver fibrosis.

Packaging

1 kg in poly bottle

2.5, 5 kg in poly drum

50, 100, 250, 500 g in poly bottle

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Code Description Quality Level mp InChI key InChI Manufacturer Form Assay Price Quantity
3577757 Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti 200 248 °C (dec.) (lit.) OVBJJZOQPCKUOR-UHFFFAOYSA-L 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2 SIGMA-ALDRICH powder 98.5-101.5% (titration)
£49.25 (exc VAT) per 100G
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3577758 Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti 200 248 °C (dec.) (lit.) OVBJJZOQPCKUOR-UHFFFAOYSA-L 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2 SIGMA-ALDRICH powder 98.5-101.5% (titration)
£295.00 (exc VAT) per 1KG
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3577759 Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti 200 248 °C (dec.) (lit.) OVBJJZOQPCKUOR-UHFFFAOYSA-L 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2 SIGMA-ALDRICH powder 98.5-101.5% (titration)
£650.00 (exc VAT) per 2.5KG
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3577760 Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti 200 248 °C (dec.) (lit.) OVBJJZOQPCKUOR-UHFFFAOYSA-L 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2 SIGMA-ALDRICH powder 98.5-101.5% (titration)
£98.38 (exc VAT) per 250G
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3577761 Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti 200 248 °C (dec.) (lit.) OVBJJZOQPCKUOR-UHFFFAOYSA-L 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2 SIGMA-ALDRICH powder 98.5-101.5% (titration)
£162.50 (exc VAT) per 500G
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3577762 Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti 200 248 °C (dec.) (lit.) OVBJJZOQPCKUOR-UHFFFAOYSA-L 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2 SIGMA-ALDRICH powder 98.5-101.5% (titration)
£30.63 (exc VAT) per 50G
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3577763 Ethylenediaminetetraacetic acid disodium salt dihydrate, (titration), reagent grade, 98.5-101.5% (ti 200 248 °C (dec.) (lit.) OVBJJZOQPCKUOR-UHFFFAOYSA-L 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2 SIGMA-ALDRICH powder 98.5-101.5% (titration)
£1,160.00 (exc VAT) per 5KG
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