ENMD-1068 HYDROCHLORIDE

ENMD-1068 HYDROCHLORIDE

Application

ENMD-1068 hydrochloride has been used as a protease-activated receptor 2 (PAR2) antagonist to determine the pathway responsible for paw edema induced by Crotalus durissus terrificus venom serine protease (Cdtsp 2).

Biochem/physiol Actions

ENMD-1068 is an antagonist of protease-activated receptor 2 (PAR2). The compound blocks TNFα production in synovial explants from patients with arthritis, and inhibits mast cell tryptase-induced recruitment of eosinophils into the pleural cavity of mice.

ENMD-1068 hydrochloride exhibits anti-angiogenic and anti-inflammatory activities.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574386 ENMD-1068 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C
£551.57 (exc VAT) per 25MG
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3574387 ENMD-1068 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C
£138.73 (exc VAT) per 5MG
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