ELOCALCITOL

ELOCALCITOL

Biochem/physiol Actions

Elocalcitol is a Vitamin D receptor (VDR) agonist and is an analog of calcitriol. Elocalcitol possesses anti-inflammatory and anti- proliferative properties. It regulates cell apoptosis and cell proliferation by binding to Vitamin D receptors (VDR). It shows a therapeutic effect on people suffering from Benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).

Elocalcitol (BX-L628) is an analog of Vitamin D3 that acts as an agonist at vitamin D VDR receptors. It has been shown to inhibit prostate cell growth and RhoA/Rho-kinase signaling. Elocalcitol (BXL-628) downregulated the expression of active RhoA and ROCK activity induced by high glucose and was shown to have renal protective effects.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576255 ELOCALCITOL white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£167.84 (exc VAT) per 1MG
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3576256 ELOCALCITOL white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£495.16 (exc VAT) per 5MG
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