DTRIM24

DTRIM24

Biochem/physiol Actions

dTRIM24, a conjugate of IACS-9571 a TRIM24 bromodomain ligand and VL-269 a VHL E3 ubiquitin ligase ligand, is a selective bifunctional degrader of bromodomain-containing transcriptional regulator TRIM24 (transcriptional intermediary factor 1a). dTRIM24 induces rapid and sustain proteasome degradation of TRIM24 in 293FT cells.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576689 DTRIM24 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£135.39 (exc VAT) per EACH
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3576690 DTRIM24 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£413.68 (exc VAT) per EACH
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