Dounce Tissue Grinder Set

Tissue grinders produce homogenates by a combination of shearing and compression actions. The tissue sample is progressively ground (sheared) into smaller pieces at the rounded end of the pestle as the spinning pestle is lowered into the tube. As the pestle is forced lower into the tube, the sample is displaced and forced between the straight outside wall of the pestle and the inside wall of the tube, compressing the tissue cells until they rupture. When the tube is pulled away from the pestle, a slight vacuum is created that pulls the sample back past the compression area, resulting in an additional homogenisation stroke. The degree of homogenisation is controlled by the clearance between the pestle's and tube's cylindrical section (radial distance usually 0.002 - 0.003 inches), the rotational speed of the pestle, and the number of compression strokes made.

Manufactured from borosilicate glass 3.3

Designed primarily for cellular work where the nucleus remains intact after homogenisation

All-glass construction

Two pestles are supplied with each complete unit

Large clearance pestle is used for the initial sample reduction

Small clearance pestle is used to form the final homogenate

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Code Description Price Quantity
2531384 Dounce Tissue Grinder Set, 100mL working volume, 232mm length
£704.52 (exc VAT) per EACH
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2531385 Dounce tissue grinder set, 2 mL complete
£241.57 (exc VAT) per EACH
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2531386 Dounce tissue grinder set, 40 mL complete
£362.85 (exc VAT) per EACH
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2531387 Dounce tissue grinder set, 15 mL complete
£254.93 (exc VAT) per EACH
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