Dextran sulfate sodium salt from Leuconostoc spp., Mr 5,000

Descriptions

Application

Dextran sulfate sodium salt from Leuconostoc sp. is a polyanion used as a test reagent for testing its capability to rupture the extracellular enveloped virus (EEV) outer membrane. It has also been used for assessing the impact of TLR4 monoclonal antibody on the growth of dextran-sulfate-sodium-(DSS)-induced colitis.

Biochem/physiol Actions

Dextran is a mixture of glucose polymers of varying size and geometry.Dextran in the form of dextran sulphate sodium acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength. The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.

Preparation Note

prepared from dextran with M_r ~5000

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	InChI key	InChI	Manufacturer	Composition	Impurities	Solubility	Form	Assay	Loss	Price		Quantity
3589274	Dextran sulfate sodium salt from Leuconostoc spp., Mr 5,000	200; 200	VZJVWSHVAAUDKD-UHFFFAOYSA-N	1S/K.Mn.4O/q+1;;;;;-1	SIGMA-ALDRICH	Sulfur Content, 16.0-20.0%	≤0.003% total nitrogen (N); ≤0.2% in water insoluble matters	H<SUB>2</SUB>O: 0.1 g/mL, clear, colorless to slightly yellow; H<SUB>2</SUB>O: freely soluble 50 mg/mL, clear	powder	≥99%	≤10% loss on drying; ≤0.2% loss on drying, 105 °C, 2 h	£370.00 (exc VAT) per 25G		- +
3589275	Dextran sulfate sodium salt from Leuconostoc spp., Mr 5,000	200; 200	VZJVWSHVAAUDKD-UHFFFAOYSA-N	1S/K.Mn.4O/q+1;;;;;-1	SIGMA-ALDRICH	Sulfur Content, 16.0-20.0%	≤0.003% total nitrogen (N); ≤0.2% in water insoluble matters	H<SUB>2</SUB>O: 0.1 g/mL, clear, colorless to slightly yellow; H<SUB>2</SUB>O: freely soluble 50 mg/mL, clear	powder	≥99%	≤10% loss on drying; ≤0.2% loss on drying, 105 °C, 2 h	£119.33 (exc VAT) per 5G		- +

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