DALCETRAPIB

DALCETRAPIB

Biochem/physiol Actions

Dalcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor. It increases HDL levels, but showed variable results on clinical outcomes. Clinical outcomes, effects on C-reactive protein and cholesterol efflux have been found to be genotype-dependent, influenced by correlated polymorphisms in the ADCY9 (adenylate cyclase type 9) gene. Positive results were obtained with AA genotype of ADCY9 gene whereas the GG genotype showed negative results and the AG genotype was neutral.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575808 DALCETRAPIB white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£586.39 (exc VAT) per 25MG
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3575809 DALCETRAPIB white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£183.86 (exc VAT) per 5MG
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