D-Luciferin, synthetic

D-Luciferin, synthetic

Application

D-Luciferin has been used in determining luciferase activity by luciferase assay in mice and Arabidopsis thaliana seeds. It has also been used in measuring bioluminescence in neonatal rat ventricular cardiomyocytes.

Substrate for firefly luciferase with a Km of approx 2 µM.

Biochem/physiol Actions

D-Luciferin uptake within the cells is regulated by the adenosine triphosphate (ATP)-binding cassette (ABC) transporter inhibitors like ATP-binding cassette transporter G2 (ABCG2)/ breast cancer resistance protein (BCRP) inhibitor fumitremorgin C. This substrate is oxidized by firefly luciferase that results in emitting a photon, which has the capability of passing through living tissues.

General description

D-Luciferin is a small molecule present abundantly in bioluminescent organisms. This molecule is sensitive to oxygen and light.

Packaging

10, 50, 100 mg in poly bottle

1, 5 mg in glass bottle

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Code Description Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3578394 D-Luciferin, synthetic 300 BJGNCJDXODQBOB-SSDOTTSWSA-N 1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1 SIGMA-ALDRICH
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3578395 D-Luciferin, synthetic 300 BJGNCJDXODQBOB-SSDOTTSWSA-N 1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1 SIGMA-ALDRICH
£717.32 (exc VAT) per 10MG
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3578396 D-Luciferin, synthetic 300 BJGNCJDXODQBOB-SSDOTTSWSA-N 1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1 SIGMA-ALDRICH
£140.68 (exc VAT) per 1MG
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3578397 D-Luciferin, synthetic 300 BJGNCJDXODQBOB-SSDOTTSWSA-N 1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1 SIGMA-ALDRICH
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3578398 D-Luciferin, synthetic 300 BJGNCJDXODQBOB-SSDOTTSWSA-N 1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1 SIGMA-ALDRICH
£422.04 (exc VAT) per 5MG
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