Cytochalasin B from Drechslera dematioidea, >=98% (HPLC), powder

Cytochalasin B from Drechslera dematioidea, >=98% (HPLC), powder

Biochem/physiol Actions

Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts.

General description

Cytochalasin B is a cell-permeable fungal toxin / mycotoxin that binds to the ′barbed′ end of actin / actin filaments. This binding leads to: Disruption of actin filaments and of interaction of actin filaments in solution Inhibition of actin polymerization Inhibition of subunit association and dissociationCytochalasin B is widely used in studies of glucose transporters (GLUT). Cytochalasin B is also used as an integral part of various in vitro micronucleus assay protocols.

Packaging

1, 5, 10, 25, 50 mg in serum bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3589946 Cytochalasin B from Drechslera dematioidea, >=98% (HPLC), powder white 300 GBOGMAARMMDZGR-TYHYBEHESA-N 1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,
£799.50 (exc VAT) per 10MG
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3589947 Cytochalasin B from Drechslera dematioidea, >=98% (HPLC), powder white 300 GBOGMAARMMDZGR-TYHYBEHESA-N 1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,
£142.07 (exc VAT) per 1MG
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3589948 Cytochalasin B from Drechslera dematioidea, >=98% (HPLC), powder white 300 GBOGMAARMMDZGR-TYHYBEHESA-N 1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,
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3589949 Cytochalasin B from Drechslera dematioidea, >=98% (HPLC), powder white 300 GBOGMAARMMDZGR-TYHYBEHESA-N 1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,
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3589950 Cytochalasin B from Drechslera dematioidea, >=98% (HPLC), powder white 300 GBOGMAARMMDZGR-TYHYBEHESA-N 1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,
£500.04 (exc VAT) per 5MG
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