CYM-5520

CYM-5520

Application

CYM-5520 has been used as a sphingosine 1-phosphate receptor 2 (S1pr2) agonist in pancreatic adenocarcinomacellline (CFPAC-1).

Biochem/physiol Actions

CYM-5520 mediates phosphorylation of transcription factor p65. It upregulates trabecular number, thickness as well as tibial bone volume density in osteoblasts.

CYM-5520 is a specific, noncompetitive allosteric agonist of sphingosine 1-phosphate receptor 2 (S1PR2; EC50 = 1.0 µM). The compound CYM-5520 does not show any agonsit activity towards S1PR1, S1PR3, S1PR4 or S1PR5.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574359 CYM-5520 white to beige 100 SIGMA-ALDRICH 2-8°C
£612.86 (exc VAT) per 25MG
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3574360 CYM-5520 white to beige 100 SIGMA-ALDRICH 2-8°C
£138.73 (exc VAT) per 5MG
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