Cyclosporin A, >=98.5%

Cyclosporin A, >=98.5%

Application

Cyclosporin A is used for immunosuppressive studies .

Biochem/physiol Actions

A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.

General description

Chemical structure: peptide

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects.

Packaging

25, 100 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

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Code Description Colour InChI key InChI Manufacturer Form Assay Price Quantity
3577570 Cyclosporin A, >=98.5% white to off-white PMATZTZNYRCHOR-CGLBZJNRSA-N 1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41( SIGMA-ALDRICH powder 97.0-101.5% (on dried basis)
£415.00 (exc VAT) per 100MG
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3577571 Cyclosporin A, >=98.5% white to off-white PMATZTZNYRCHOR-CGLBZJNRSA-N 1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41( SIGMA-ALDRICH powder 97.0-101.5% (on dried basis)
£135.00 (exc VAT) per 25MG
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