CRISABOROLE

CRISABOROLE

Biochem/physiol Actions

Crisaborole is a non-steroidal anti-inflammatory phosphodiesterase 4 (PDE4) inhibitor. Crisaborole has an IC50 value of 490 nM for PDE4 with similar IC50 values for release of cytokines TNF-α, IL-2, and IFN-γ, and shows little inhibition against other PDE isozymes. Crisaborole has been approved as a topical treatment for atopic dermatitis.

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Solubility Form Assay Price Quantity
3573563 CRISABOROLE white to beige 100 SIGMA-ALDRICH DMSO: 10 mg/mL, clear
£490.29 (exc VAT) per 25MG
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3573564 CRISABOROLE white to beige 100 SIGMA-ALDRICH DMSO: 10 mg/mL, clear
£150.43 (exc VAT) per 5MG
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