CP-424174

CP-424174

Biochem/physiol Actions

CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Solubility Form Assay Price Quantity
3573794 CP-424174 white to beige 100 SIGMA-ALDRICH DMSO: 20 mg/mL, clear
£536.25 (exc VAT) per 25MG
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3573795 CP-424174 white to beige 100 SIGMA-ALDRICH DMSO: 20 mg/mL, clear
£131.76 (exc VAT) per 5MG
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