Conduritol B epoxide,

Conduritol B epoxide,

Application

Conduritol B epoxide has been used as an inhibitor of GBA1 to discriminate between acid ?-glucosidase (GBA1) and non-lysosomal ?-glucosidase (GBA2) activity in ?-glucosidase activity assay. It has also been used as a selective glucocerebrosidase (GCase) inhibitor.

Biochem/physiol Actions

Conduritol B epoxide(CBE)is capable of inactivating sucrase-isomaltase irreversibly. It can be used to produce cell and animal models to study on Gaucher disease (GD) and Parkinson?s disease (PD).

β-Glucosidase inhibitor

General description

Conduritol B epoxide(CBE) is a mix of 1-L-1,2-anhydro-myo-inositol and 1-D-1,2-anhydro-myo-inositol.

Packaging

5, 25 mg in glass insert

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Code Description Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3586689 Conduritol B epoxide, 100 ZHMWOVGZCINIHW-UHFFFAOYSA-N 1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H SIGMA-ALDRICH
£678.32 (exc VAT) per 25MG
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3586690 Conduritol B epoxide, 100 ZHMWOVGZCINIHW-UHFFFAOYSA-N 1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H SIGMA-ALDRICH
£197.79 (exc VAT) per 5MG
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