Concanavalin A from Canavalia ensiformis (Jack bean), Type VI, lyophilized powder

Descriptions

Analysis Note

Agglutination activity: Determined from serial dilutions of a 1 mg/mL solution (this activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C). Requires Type A Human Blood.

Application

Concanavalin A from Canavalia ensiformis (Jack bean) has been used for developing zwitterion-immobilized molecularly imprinted polymers (ziMIPs) for protein crystallization. It has been also used in the preparation of protein loaded microgels to prevent enzymatic degradation of microgels for monitoring by confocal laser scanning microscope (CLSM).

Biochem/physiol Actions

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Packaging

1 g in poly bottle

25, 100, 250 mg in poly bottle

Preparation Note

Highly purified by specific affinity chromatography.

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	Manufacturer	Storage Temp.	Impurities	Solubility	Form	Price	Quantity
3587094	Concanavalin A from Canavalia ensiformis (Jack bean), Type VI, lyophilized powder	200	SIGMA-ALDRICH	−20°C	salt, essentially free, Carbohydrate, essentially free	water: 1 % (w/v)	lyophilized powder	£109.76 (exc VAT) per 100MG	- +
3587095	Concanavalin A from Canavalia ensiformis (Jack bean), Type VI, lyophilized powder	200	SIGMA-ALDRICH	−20°C	salt, essentially free, Carbohydrate, essentially free	water: 1 % (w/v)	lyophilized powder	£753.54 (exc VAT) per 1G	- +
3587096	Concanavalin A from Canavalia ensiformis (Jack bean), Type VI, lyophilized powder	200	SIGMA-ALDRICH	−20°C	salt, essentially free, Carbohydrate, essentially free	water: 1 % (w/v)	lyophilized powder	£185.25 (exc VAT) per 250MG	- +
3587097	Concanavalin A from Canavalia ensiformis (Jack bean), Type VI, lyophilized powder	200	SIGMA-ALDRICH	−20°C	salt, essentially free, Carbohydrate, essentially free	water: 1 % (w/v)	lyophilized powder	£38.16 (exc VAT) per 25MG	- +