CL075

CL075

Application

CL075 has been used to activate the monocyte-derived dendritic cells (DCs) to demonstrate the ability of DCs to induce cell death.

Biochem/physiol Actions

CL075 is a thiazoloquinolone derivative. It might influence tumor development.

CL075 is a selective agonist of Toll-like receptor-8 (TLR-8) with immunostimulant activity. It showed an EC50 value of 400nM for IRF-NFκB stimulation in TLR8 compared to 4 µM for TLR7.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576009 CL075 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£444.32 (exc VAT) per 25MG
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3576010 CL075 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£137.75 (exc VAT) per 5MG
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