CILENGITIDE TRIFLUOROACETIC ACID SALT

CILENGITIDE TRIFLUOROACETIC ACID SALT

Application

Cilengitide trifluoroacetic acid salt has been used as an inhibitor of integrin ?v?5.

Biochem/physiol Actions

It exhibits antitumor activity in glioblastoma multiforme tumors. Integrins are heterodimers of ? and ? chain. They are transmembrane receptors which are responsible for cell-to-cell and cell-extracellular matrix interactions. They control tumor angiogenesis, invasion and migration.

Cilengitide is a vascular targeting agent (VTA) that acts as an integrin antagonist. Cilengitide is a cyclized Arg-Gly-Glu(RGD)-containing pentapeptide that selectively blocks activation of the Avβ3 and Avβ5 integrins.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575128 CILENGITIDE TRIFLUOROACETIC ACID SALT white to beige 100 SIGMA-ALDRICH −20°C
£785.57 (exc VAT) per 25MG
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3575129 CILENGITIDE TRIFLUOROACETIC ACID SALT white to beige 100 SIGMA-ALDRICH −20°C
£254.89 (exc VAT) per 5MG
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