Cathepsin D from bovine spleen, lyophilized powder, >=2.0 units/mg protein

Cathepsin D from bovine spleen, lyophilized powder, >=2.0 units/mg protein

Biochem/physiol Actions

Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer’;s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced.

Packaging

5, 10, 20, 40 units in serum bottle

Physical form

Lyophilized powder containing citrate buffer salts

Unit Definition

One unit will produce an increase in A280 of 1.0 per min per mL at pH?3.0 at 37?°C measured as TCA-soluble products using hemoglobin as substrate (1 cm light path).

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Code Description Quality Level Manufacturer Storage Temp. Form Price Quantity
3589853 Cathepsin D from bovine spleen, lyophilized powder, >=2.0 units/mg protein 200 SIGMA-ALDRICH −20°C lyophilized powder
£546.00 (exc VAT) per EACH
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+
3589854 Cathepsin D from bovine spleen, lyophilized powder, >=2.0 units/mg protein 200 SIGMA-ALDRICH −20°C lyophilized powder
£970.82 (exc VAT) per EACH
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+
3589855 Cathepsin D from bovine spleen, lyophilized powder, >=2.0 units/mg protein 200 SIGMA-ALDRICH −20°C lyophilized powder
£320.36 (exc VAT) per EACH
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+