Caspofungin, aechinocandin, a lipophilic antifungal drug and ? ?-1,3-D-glucan synthesis antagonist, is used in fungal cell wall biosynthesis research to study the role of ?-1,3-D-glucans in cell wall integrity and fungal survival under various environmental and chemical stresses.
Biochem/physiol Actions
Caspofungin is an echinocandin antifungal that inhibits 1,3-β-D-glucan synthase, which is required for cell wall synthesis, thereby disturbing the integrity of the fungal cell wall.