CA3

CA3

Biochem/physiol Actions

CA3 is a potent and selective inhibitor of YAP1 (Hippo co-activator Yes-associated protein 1) that inhibits YAP1 expression and transcriptional activity in esophageal adenocarcinoma (EAC) cell lines. CA3 potently inhibits growth, induces apoptosis in radiation resistant CSC (cancer stem cell) enriched EAC cells. It inhibits tumor growth of in xenograft model with no apparent toxicity.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576636 CA3 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£388.61 (exc VAT) per EACH
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3576637 CA3 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£119.93 (exc VAT) per EACH
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