BIM5078

BIM5078

Biochem/physiol Actions

BIM5078 is a potent Hepatocyte nuclear factor 4a (HNF4a) antagonist that directly binds to ligand-binding pocket and modulates the expression of known HNF4a target genes. BIM5078 also inhibits insulin gene expression by disruption of E47 and PDX-1 binding to insulin promoter. BIM5078 is selectively cytotoxic to transformed cells.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574098 BIM5078 white to beige 100 DLUVMRPVZILBOE-UHFFFAOYSA-N 1S/C14H10ClN3O4S/c1-9-16-12-4-2-3-5-13(12)17(9)23(21,22)14-8-10(18(19)20)6-7-11(14)15/h2-8H,1H3 SIGMA-ALDRICH DMSO: 10 mg/mL, clear (warmed) powder ≥98% (HPLC)
£619.82 (exc VAT) per 25MG
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3574099 BIM5078 white to beige 100 DLUVMRPVZILBOE-UHFFFAOYSA-N 1S/C14H10ClN3O4S/c1-9-16-12-4-2-3-5-13(12)17(9)23(21,22)14-8-10(18(19)20)6-7-11(14)15/h2-8H,1H3 SIGMA-ALDRICH DMSO: 10 mg/mL, clear (warmed) powder ≥98% (HPLC)
£162.96 (exc VAT) per 5MG
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