BEVIRIMAT

BEVIRIMAT

Biochem/physiol Actions

Bevirimat is the first in class HIV maturation inhibitor. It acts by inhibiting the processing of the Gag capsid (CA)/spacer peptide 1 (SP1), which causes accumulation of CA/SP1 (p25) precursor proteins and blocks maturation of the viral core particle.

It also causes defective core condensation and releases the non-infectious virus particles from cells infected with human immunodeficiency virus (HIV). Thus, bevirimat blocks the spread of HIV infection to other cells.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575761 BEVIRIMAT white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£575.25 (exc VAT) per 25MG
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3575762 BEVIRIMAT white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£151.82 (exc VAT) per 5MG
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