beraprost sodium

Biochem/physiol Actions

Beraprost sodium is used as a therapeutic agent for chronic artery obstructions or primary pulmonary hypertension. In individuals with coronary artery disease, beraprost sodium helps to reduce oxidative stress and developed forearm endothelium dependent vasodilation.

Beraprost sodium is a chemically stable analog of prostacyclin PGI2. As other prostanoids, beraprost is a potent vasodilator and possesses antithrombotic, antiproliferative and anti-inflammatory properties. Beraprost sodium activates prostaglandin I (IP) receptor, which is coupled with Gs proteins and activates adenylate cyclase. It has been studied for the treatment of pulmonary hypertension.

General description

Beraprost sodium is an orally active prostacyclin analog.

Packaging

1, 5 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575326 beraprost sodium white to beige 100 YTCZZXIRLARSET-UEIGIMKUSA-M 1S/C24H30O5.Na/c1-3-4-7-15(2)19(25)13-12-17-20(26)14-21-23(17)18-10-5-8-16(24(18)29-21)9-6-11-22(27)28;/h5,8,10,12-13,15,17,19-21,23,25-26H,6-7,9,11,14H2,1-2H3 SIGMA-ALDRICH &minus;20&deg;C H<SUB>2</SUB>O: 20 mg/mL, clear powder &ge;98% (HPLC)
£167.14 (exc VAT) per 1MG
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3575327 BERAPROST SODIUM white to beige 100 YTCZZXIRLARSET-UEIGIMKUSA-M 1S/C24H30O5.Na/c1-3-4-7-15(2)19(25)13-12-17-20(26)14-21-23(17)18-10-5-8-16(24(18)29-21)9-6-11-22(27)28;/h5,8,10,12-13,15,17,19-21,23,25-26H,6-7,9,11,14H2,1-2H3 SIGMA-ALDRICH &minus;20&deg;C H<SUB>2</SUB>O: 20 mg/mL, clear powder &ge;98% (HPLC)
£667.18 (exc VAT) per 5MG
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