BAY-707

Biochem/physiol Actions

BAY-707 is an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1), which hydrolyzes oxidized purine nucleoside triphosphates that might otherwise be incorporated into DNA/RNA and contribute to DNA damage. BAY-707 was shown to be a substrate-competitive, selective MTH1 inhibitor with an IC50 value of 2.3 nM.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576180 BAY-707 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£562.71 (exc VAT) per 25MG
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3576181 BAY-707 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£145.55 (exc VAT) per 5MG
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