BAM15

BAM15

Biochem/physiol Actions

BAM15 increases mitochondrial respiration rate and is also found to be less cytotoxic compared to other protonophore uncouplers such as carbonyl cyanide p-trifluoromethoxyphenylhydrazone. Hindered oncogenic MAPK (mitogen-activated protein kinase ) signaling leads to BAM15 induced mitochondrial apoptotic pathway activation.

BAM15 is a cell penetrant and potent uncoupler of oxidative phosphorylation in mitochondria that that does not depolarizes the plasma membrane. BAM15 protects mice from acute renal ischemic-reperfusion injury.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575349 BAM15 white to beige 100 SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£607.29 (exc VAT) per 25MG
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3575350 BAM15 white to beige 100 SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£150.43 (exc VAT) per 5MG
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