ARAMCHOL

ARAMCHOL

Biochem/physiol Actions

Aramchol is a bile salt fatty acid conjugate (BAFAC) of arachidic acid and cholic acid. It has been shown to reduce liver fat by a dual mechanism of action. It inhibits the activity of liver stearoyl coenzyme A desaturase 1 (SCD1), decreasing the synthesis of fatty acids. In addition, it activates cholesterol efflux by stimulating the adenosine triphosphate–binding cassette transporter A1 (ABCA1). Aramchol has been investigated for treatment for nonalcoholic steatohepatitis, or NASH.

Arachidyl amido cholanoic acid (Aramchol) is a cholesterol solubilizer that has the potential to prevent and dissolves cholesterol gallstones in inbred mice and in human gallbladder bile ex vivo.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576188 ARAMCHOL white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£401.14 (exc VAT) per 25MG
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3576189 ARAMCHOL white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£124.24 (exc VAT) per 5MG
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