ANI-7

ANI-7

Biochem/physiol Actions

ANI-7 is a potent and selective activator of the aryl hydrocarbon receptor (AHR) pathway that exhibit potent cytotoxic activity against multiple cancer cell lines while spearing normal breast cells (MCF-10A). Apparently activation of AHR by ANI-7 leads to induction of CYP1 metabolising monooxygenases. ANI-7 metabolites induce DNA damage, checkpoint activation, S-phase cell cycle arrest and cell death in sensitive breast cancer cell lines.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576097 ANI-7 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£380.25 (exc VAT) per 25MG
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3576098 ANI-7 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£99.45 (exc VAT) per 5MG
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