AMBRISENTAN

AMBRISENTAN

Biochem/physiol Actions

Ambrisentan is an endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It is 200-fold selective for the the ETA receptor subtype with a Ki of 1 nM for ETA and a Ki of 195 nM for ETB.

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Code Description Colour InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3575826 AMBRISENTAN white to beige OUJTZYPIHDYQMC-UHFFFAOYSA-N 1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26) SIGMA-ALDRICH DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£178.29 (exc VAT) per 10MG
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3575827 AMBRISENTAN white to beige OUJTZYPIHDYQMC-UHFFFAOYSA-N 1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26) SIGMA-ALDRICH DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£612.86 (exc VAT) per 50MG
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