ACOTIAMIDE DIHYDROCHLORIDE

Biochem/physiol Actions

Acotiamide is a potent, selective and reversible inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide showed no affinity for dopamine D2 or serotonin 5-HT4 receptors but does have activity as a muscarinic antagonist. It acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonism, and has been used for the treatment of functional dyspepsia (FD) involving gastric motility dysfunction.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575100 ACOTIAMIDE DIHYDROCHLORIDE white to beige 100 SIGMA-ALDRICH −20°C H2O: 20 mg/mL, clear powder ≥98% (HPLC)
£388.61 (exc VAT) per 25MG
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3575101 ACOTIAMIDE DIHYDROCHLORIDE white to beige 100 SIGMA-ALDRICH −20°C H2O: 20 mg/mL, clear powder ≥98% (HPLC)
£99.59 (exc VAT) per 5MG
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