ABC1183

ABC1183

Biochem/physiol Actions

ABC1183 is an orally active, potent and selective inhibitor of GSK3 α/β and CDK9, which induces G2/M cell cycle arrest and apoptosis in cancer cells. Apparently ABC1183 suppresses tumor growth and inflammation-driven gastrointestinal disease symptoms due to down regulation of TNFα and IL-6 pro-inflammatory cytokines. It does not exhibit organ or hematological toxicities.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576598 ABC1183 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£388.61 (exc VAT) per EACH
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3576599 ABC1183 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£90.26 (exc VAT) per EACH
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