4-Methylpyrazole hydrochloride, alcohol dehydrogenase inhibitor

Descriptions

Application

Useful as an antidote in methanol and ethylene glycol poisoning.

4-Methylpyrazole hydrochloride has been used: as a cytochrome P450 2E1 inhibitoras cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cellsto inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells

Biochem/physiol Actions

4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models.

Alcohol dehydrogenase inhibitor

Packaging

100, 500 mg in poly bottle

1 g in poly bottle

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	mp	InChI key	InChI	Manufacturer	Form	Assay	Price	Quantity
3577840	4-Methylpyrazole hydrochloride, alcohol dehydrogenase inhibitor	200	157-159 °C	PUCXJHNDMYZOHG-UHFFFAOYSA-N	1S/C4H6N2.ClH/c1-4-2-5-6-3-4;/h2-3H,1H3,(H,5,6);1H	SIGMA-ALDRICH	powder	≥95%	£97.36 (exc VAT) per 100MG	- +
3577841	4-Methylpyrazole hydrochloride, alcohol dehydrogenase inhibitor	200	157-159 °C	PUCXJHNDMYZOHG-UHFFFAOYSA-N	1S/C4H6N2.ClH/c1-4-2-5-6-3-4;/h2-3H,1H3,(H,5,6);1H	SIGMA-ALDRICH	powder	≥95%	£536.25 (exc VAT) per 1G	- +
3577842	4-Methylpyrazole hydrochloride, alcohol dehydrogenase inhibitor	200	157-159 °C	PUCXJHNDMYZOHG-UHFFFAOYSA-N	1S/C4H6N2.ClH/c1-4-2-5-6-3-4;/h2-3H,1H3,(H,5,6);1H	SIGMA-ALDRICH	powder	≥95%	£338.46 (exc VAT) per 500MG	- +