3-Nitro-L-tyrosine, crystalline

3-Nitro-L-tyrosine, crystalline

Application

3-Nitro-L-tyrosine has been used in:western blot analysis to quantify the nitrotyrosine levels in mice tissue proteinMurashige–Skoog medium to treat wild type and mitogen-activated protein kinase 6 (mpk6)-2 mutant seedlings for inferring the connection between nitric oxide (NO) and MPK6 functions in the regulation of mitotic microtubule organizationimmunocytochemistry

Biochem/physiol Actions

3-Nitro-L-tyrosine is an oxidant and cytotoxic agent. 3-Nitrotyrosine serves as a biological marker of proteins modified by nitrogen-free radical species in systemic autoimmunogenic conditions. It is a marker for oxidative damage mediated by peroxynitrite. Nitrotyrosine is associated with VEGF-C expression and lymph node metastasis in breast cancer. 3-Nitrotyrosine is produced due to oxidative/nitrosative stress-mediated chemical modifications such as nitration of proteins, which is observed in lung carcinogenesis.

Packaging

5, 10, 25 g in poly bottle

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Code Description Quality Level mp InChI key InChI Manufacturer Form Price Quantity
3591877 3-Nitro-L-tyrosine, crystalline 200 233-235 °C (dec.) (lit.) FBTSQILOGYXGMD-LURJTMIESA-N 1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1 SIGMA-ALDRICH crystalline
£186.64 (exc VAT) per 10G
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3591878 3-Nitro-L-tyrosine, crystalline 200 233-235 °C (dec.) (lit.) FBTSQILOGYXGMD-LURJTMIESA-N 1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1 SIGMA-ALDRICH crystalline
£409.50 (exc VAT) per 25G
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3591879 3-Nitro-L-tyrosine, crystalline 200 233-235 °C (dec.) (lit.) FBTSQILOGYXGMD-LURJTMIESA-N 1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1 SIGMA-ALDRICH crystalline
£101.26 (exc VAT) per 5G
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