3-Isobutyl-1-methylxanthine, BioUltra, >=99%

3-Isobutyl-1-methylxanthine, BioUltra, >=99%

Application

3-Isobutyl-1-methylxanthine, an inhibitor of adenosine 3?,5?-cyclic monophosphate phosphodiesterase (cAMP PDE), has been used:for adipogenic differentiationin tissue culture3T3-L1 preadipocyte differentiation(

Biochem/physiol Actions

The increase in cAMP level as a result of phosphodiesterase inhibition by IBMX activates PKA, leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50: 1.3 µM). IBMX also serves as an adenosine receptor antagonist. IBMX has been shown to inhibit ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. IBMX induces calcium release from intracellular stores in sensory neurons.

Features and Benefits

Trace element testing by ICP ICP testing for trace sulfur (as sulfate) and phosphorus (as phosphate) content Ion chromatography testing for trace ammonium content

Packaging

1 g in poly bottle

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Code Description InChI key InChI Manufacturer Impurities Assay Price Quantity
3577821 3-Isobutyl-1-methylxanthine, BioUltra, >=99% APIXJSLKIYYUKG-UHFFFAOYSA-N 1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) SIGMA-ALDRICH ﹤0.005% Phosphorus (P)
£112.82 (exc VAT) per 100MG
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3577822 3-Isobutyl-1-methylxanthine, BioUltra, >=99% APIXJSLKIYYUKG-UHFFFAOYSA-N 1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) SIGMA-ALDRICH ﹤0.005% Phosphorus (P)
£585.00 (exc VAT) per 1G
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3577823 3-Isobutyl-1-methylxanthine, BioUltra, >=99% APIXJSLKIYYUKG-UHFFFAOYSA-N 1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) SIGMA-ALDRICH ﹤0.005% Phosphorus (P)
£195.00 (exc VAT) per 250MG
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