1S;3R-RSL 3

1S;3R-RSL 3

Application

1S,3R-RSL 3 has been used:as a glutathione peroxidase 4 (GPX4) inhibitor to study its effects on cell death in subventricular glioblastoma multiforme (GBM) linesGPX4 inhibitor and ferroptosis inducer to study its effects on cardiomyocyte death and heart failure in miceas a ferroptosis inducer in HT-1080 cellsin cell viability assay

Biochem/physiol Actions

RSL3 is an inducer of ferroptosis. It acts by a different method than erastin to induce ferroptosis by inhibiting glutathione peroxidase 4 (GPX4).

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576007 1S;3R-RSL 3 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£565.50 (exc VAT) per 25MG
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3576008 1S;3R-RSL 3 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£139.29 (exc VAT) per 5MG
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