(2S,3S)-Hydroxybupropion hydrochloride, >=98% (HPLC)

Biochem/physiol Actions

(2S,3S)-hydroxybupropion is a dopamine transporter (DAT) and norepinephrine transporter (NET) transporters inhibitor and nicotinic acetylcholine receptor (nAChR) family modulator. Hydroxybupropions were reported to contribute to antidepressant and perhaps smoking cessation activities. Both (2S,3S) and (2R,3R) metabolites reverse affective and somatic withdrawal signs in nicotine-dependent mice, but (2S,3S)-hydroxybupropion is more potent. (2S,3S)-hydroxybupropion significantly decreases the development of nicotine reward in mice.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

(2S,3S)-hydroxybupropion is a major metabolite of bupropion.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3573394 (2S,3S)-Hydroxybupropion hydrochloride, >=98% (HPLC) white to tan 100 ORXTVTDGPVINDN-BTJVGWIPSA-N 1S/C13H18ClNO2.ClH/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10;/h4-7,9,15-16H,8H2,1-3H3;1H/t9-,13+;/m0./s1
£732.64 (exc VAT) per 25MG
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3573395 (2S,3S)-Hydroxybupropion hydrochloride, >=98% (HPLC) white to tan 100 ORXTVTDGPVINDN-BTJVGWIPSA-N 1S/C13H18ClNO2.ClH/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10;/h4-7,9,15-16H,8H2,1-3H3;1H/t9-,13+;/m0./s1
£196.39 (exc VAT) per 5MG
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