MONOCLONAL PAX-5 (24)

Descriptions

General description

PAX-5 encodes for B-cell-specific activator protein (BSAP), a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5. PAX-5 is not detected in multiple myeloma and solitary plasmacytoma, making it useful for such differentiation. Diffuse large B-cell lymphomas do express PAX-5, save for those with terminal B-cell differentiation. T-cell neoplasms do not stain with anti-PAX-5. There is a strong association with CD20 expression.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

PAX-5 Positive Control Slides, Product No. 312S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

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Quality

IVD

RUO

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	Manufacturer	Further Info	Storage Temp.	Form	Price	Quantity
3572972	MONOCLONAL PAX-5 (24)	100; 500	SIGMA-ALDRICH	For In Vitro Diagnostic Use in Select Regions (See Chart)	2-8°C	buffered aqueous solution	£268.17 (exc VAT) per EACH	- +
3572973	MONOCLONAL PAX-5 (24)	100; 500	SIGMA-ALDRICH	For In Vitro Diagnostic Use in Select Regions (See Chart)	2-8°C	buffered aqueous solution	£676.11 (exc VAT) per EACH	- +
3572974	MONOCLONAL PAX-5 (24)	100; 500	SIGMA-ALDRICH	For In Vitro Diagnostic Use in Select Regions (See Chart)	2-8°C	buffered aqueous solution	£1,048.31 (exc VAT) per EACH	- +