MONOCLONAL GLUCAGON (EP74)

Descriptions

General description

The normal islets of Langerhans (pancreas) contain four major?cell types, 15-20% of which are alpha cells which produce glucagon.¹ Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome² (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.³Immunohistochemically, the two types of glucagonomas are reactive to the glucagon antibody, though occasionally only weakly.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

Glucagon Positive Control Slides, Product No. 259S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide.

Preparation Note

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Quality

IVD

RUO

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	Manufacturer	Further Info	Storage Temp.	Form	Price	Quantity
3572933	MONOCLONAL GLUCAGON (EP74)	100; 500	SIGMA-ALDRICH	(For In Vitro Diagnostic Use in Select Regions (See Chart))	2-8°C	buffered aqueous solution	£242.16 (exc VAT) per EACH	- +
3572934	MONOCLONAL GLUCAGON (EP74)	100; 500	SIGMA-ALDRICH	(For In Vitro Diagnostic Use in Select Regions (See Chart))	2-8°C	buffered aqueous solution	£612.73 (exc VAT) per EACH	- +
3572935	MONOCLONAL GLUCAGON (EP74)	100; 500	SIGMA-ALDRICH	(For In Vitro Diagnostic Use in Select Regions (See Chart))	2-8°C	buffered aqueous solution	£955.65 (exc VAT) per EACH	- +
3572936	MONOCLONAL GLUCAGON (EP74)	100; 500	SIGMA-ALDRICH	(For In Vitro Diagnostic Use in Select Regions (See Chart))	2-8°C	buffered aqueous solution	£198.29 (exc VAT) per EACH	- +
3572937	MONOCLONAL GLUCAGON (EP74)	100; 500	SIGMA-ALDRICH	(For In Vitro Diagnostic Use in Select Regions (See Chart))	2-8°C	buffered aqueous solution	£417.69 (exc VAT) per EACH	- +