CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation.Endothelial cells also express this marker; therefore, antibodies to CD31 have been used as a tool to identify the vascular origin of neoplasms.1-3Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells.4Staining of nonvascular tumors (excluding hematopoietic neoplasms) has not been observed.
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
Linkage
CD31 Positive Control Slides, Product No. 131S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide.
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.