BCL6 (EP278)

BCL6 (EP278)

General description

BCL6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein.1 In normal tissue these antibodies have strong nuclear staining for a subset of B-lymphocytes, mostly located in germinal centers (GC).2 BCL6 antibodies stain malignant cells in follicular lymphoma,3 diffuse large B-cell lymphomas,4 Burkitt lymphoma,4 classical Hodgkin lymphoma,5 as well as majority of tumor cells in nodular lymphocyte predominant Hodgkin lymphoma.6 BCL6 expression has been also seen in anaplastic large cell lymphomas (ALCL).7

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

BCL6 Positive Control Slides, Product No. 227S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide.

Preparation Note

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Quality

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Code Description Manufacturer Further Info Form Price Quantity
3572901 BCL6 (EP278); 1ml; Predilute SIGMA-ALDRICH (For In Vitro Diagnostic Use in Select Regions (See Chart)) buffered aqueous solution
£211.28 (exc VAT) per EACH
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